View source for Sandbox CsrA

==CsrA==
<Structure load='1vpz' size='500' frame='true' align='right' caption='CsRA (Pseudomonas aeruginosa)' scene='Sandbox_CsrA/Default/4' />

Residues 24-27 form a <scene name='Sandbox_CsrA/Rna/6'>putative RNA-binding motif</scene><ref>PMID: 16104018</ref>. <br>


<scene name='Sandbox_CsrA/Two_mutant_sites/4'>AO and AL mutant sites</scene>


{{Template:Checkbox Toggle CsrRNABinding}}
===Residues Highlighted by Alanine Scanning Mutation of CsrA<ref name="Alanine"> PMID:16923806 </ref>===
{{Template:Checkbox Toggle Csr19}}<br>
{{Template:Checkbox Toggle Csr28}} 



<scene name='Sandbox_CsrA/Default/3'>Reset to Initial Scene</scene><br>
{{Link Toggle FancyCartoonHighQualityView}}



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==E. coli CsrA==
<Structure load='Image:1y00model1.pdb' size='500' frame='true' align='right' caption='CsRA (E. coli)' scene='Sandbox_CsrA/1y00default/1' />


{{Template:Checkbox Toggle CsrRNABinding}}
===Residues Highlighted by Alanine Scanning Mutation of CsrA<ref name="Alanine" />===
{{Template:Checkbox Toggle Csr19}}<br>
{{Template:Checkbox Toggle Csr28}} 



<scene name='Sandbox_CsrA/Default/3'>Reset to Initial Scene</scene><br>
{{Link Toggle FancyCartoonHighQualityView}}



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==Aligned CsrA structures==
<Structure load='Image:1y00model1.pdb' size='500' frame='true' align='right' caption='CsRA structures aligned' scene='Sandbox_CsrA/Csrapdbs/6' />





{{Template:Checkbox Toggle CsrRNABinding}}
===Residues Highlighted by Alanine Scanning Mutation of CsrA<ref name="Alanine" />===
{{Template:Checkbox Toggle Csr19}}<br>
{{Template:Checkbox Toggle Csr28}} 


===Aligned Structures===
Display <scene name='Sandbox_CsrA/Csrapdbs/6'>cartoon representation of aligned CsrA structures</scene>.<br>
{{Template:Checkbox Toggle Model1Cartoon}} (<font color="cyan">'''E. coli'''</font>) <br>
{{Template:Checkbox Toggle Model2Cartoon}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br>
{{Template:Checkbox Toggle Model3Cartoon}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br>

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Display <scene name='Sandbox_CsrA/Csrapdbs/5'>backbone trace of aligned CsrA structures</scene>.<br>
{{Template:Checkbox Toggle Model1BackboneTrace}} (<font color="cyan">'''E. coli'''</font>) <br>
{{Template:Checkbox Toggle Model2BackboneTrace}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br>
{{Template:Checkbox Toggle Model3BackboneTrace}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br>
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==Model of Vibrio CsrA==
<table style="background-color:#ffffc0" cellpadding="8" width="95%" border="0"><tr><td valign='top'>[[Image:Note.gif|left]]  '''Theoretical Model:'''
The protein structure described in this section was determined [[theoretical models|theoretically]], and hence should be interpreted with caution.</td></tr></table>

<Structure load='Image:VfischeriCsrA2dimer.pdb' size='500' frame='true' align='right' caption='CsRA (V. fischeri)' scene='Sandbox_CsrA/Vibriomodel/1' />


{{Template:Checkbox Toggle CsrRNABinding}}
===Residues Highlighted by Alanine Scanning Mutation of CsrA<ref name="Alanine" />===
{{Template:Checkbox Toggle Csr19}}<br>
{{Template:Checkbox Toggle Csr28}} 



{{Link Toggle FancyCartoonHighQualityView}}





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==Aligned CsrA structures and Vibrio Model==
<table style="background-color:#ffffc0" cellpadding="8" width="95%" border="0"><tr><td valign='top'>[[Image:Note.gif|left]]  '''Theoretical Model:'''
The ''Vibrio'' structure described in this section was determined [[theoretical models|theoretically]], and hence should be interpreted with caution.</td></tr></table>
<Structure load='1vpz' size='500' frame='true' align='right' caption='CsRA structures aligned' scene='Sandbox_CsrA/Structuresplusmodel/5' />

{{Template:Checkbox Toggle CsrRNABinding}}

===Residues Highlighted by Alanine Scanning Mutation of CsrA<ref name="Alanine" />===
{{Template:Checkbox Toggle Csr19}}<br>
{{Template:Checkbox Toggle Csr28}} 


===Aligned Structures===
Display <scene name='Sandbox_CsrA/Structuresplusmodel/5'>cartoon representation of aligned CsrA structures</scene>.<br>
{{Template:Checkbox Toggle Model1Cartoon}} (<font color="cyan">'''E. coli'''</font>) <br>
{{Template:Checkbox Toggle Model2Cartoon}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br>
{{Template:Checkbox Toggle Model3Cartoon}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br>
{{Template:Checkbox Toggle Model4Cartoon}} (<font color="magenta">'''Vibrio fischeri'''</font>)<br>

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Display <scene name='Sandbox_CsrA/Structuresplusmodel/6'>backbone trace of aligned CsrA structures</scene>.<br>
{{Template:Checkbox Toggle Model1BackboneTrace}} (<font color="cyan">'''E. coli'''</font>) <br>
{{Template:Checkbox Toggle Model2BackboneTrace}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br>
{{Template:Checkbox Toggle Model3BackboneTrace}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br>
{{Template:Checkbox Toggle Model4BackboneTrace}} (<font color="magenta">'''Vibrio fischeri'''</font>)<br>


==Structures Used On This Page==
[[1y00]] is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y00 OCA]. 

[[1vpz]] is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPZ OCA]. 

[[2bti]] is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BTI OCA]. 

==See Also==
[[1t3o]] - NMR structure of ''Bacillus subtilis'' CsrA

==References==
<references/>