View source for HypA-HypB-HypC-HypD-HypE-HypF

<StructureSection load='2z1d' size='340' side='right' caption='HypD with Fe4S4 center (PDB code [[2z1d]])' scene=''>
== Function ==
The [NiFe] hydrogenase or '''hydrogenase expression/formation protein''' contains a NiFe(CO)(CN)2 in its reaction center.  '''HypA, HypB, HypC, HypD, HypE and HypF''' are required for the maturation of [NiFe] hydrogenase. 
*'''HypA'''<ref>PMID:15995183</ref> and '''HypB'''<ref>PMID:9140970</ref> are involved in the insertion of Ni atom.  For more details of HypA see [[Molecular Playground/HypA]].
*'''HypE''' and '''HypF'''<ref>PMID:15291820</ref> catalyze the biosynthesis of the CN ligand.  
*'''HypC''' and '''HypD'''<ref>PMID:15504408</ref> deliver the Fe and CO to the hydrogenase active center.  

== 3D Structures of HypA, HypB, HypC, HypD, HypE and HypF ==
[[HypA, HypB, HypC, HypD, HypE and HypF 3D structures]]

</StructureSection>

== References ==
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[[Category:Topic Page]]