View source for C-terminal domain of the DEAD-box protein Dbp5

<StructureSection load="3gfp" size="400" color="" frame="true"  spin="on" Scene=  side="right" | CAPTION="Yeast DEAD box protein 5 C-terminal domain [[3gfp]]" >
[[Image:3gfp.png|left|200px]]

===Structure of the C-terminal domain of the DEAD-box protein Dbp5 ([[3gfp]])===
'''(see also [[Helicase]])'''

{{ABSTRACT_PUBMED_19805289}}

==About this Structure== 
3GFP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GFP OCA]. 


The C-terminal domain  of Dbp5 is a RecA-like fold, displayed here similar to [http://www.pnas.org/content/106/38/16251/F1.expansion.html figure 1A] of [http://www.pnas.org/content/106/38/16251.long the paper describing the structure]:
*<scene name='3gfp/Front/1'>Front orientation</scene> of the C-terminal domain of Dbp5. {{Link Toggle FancyCartoonHighQualityView}}.
*<scene name='3gfp/Back/2'>Back orientation</scene>.


<scene name='3gfp/Figure2c/4'>Surface residues targeted for site-directed mutagenesis</scene> to see if they affect interaction with Gle1. See [http://www.pnas.org/content/106/38/16251/F2.expansion.html figure 2C] of [http://www.pnas.org/content/106/38/16251.long the paper describing the structure].

<scene name='3gfp/Twoelements/4'>The Dbp5 C-terminal domain possesses two elements</scene> that are not present in the corresponding domain of other structurally characterized DExD/H-box proteins: an extended loop element after strand β5 and a conserved α-helix at its C-terminus, both shown in red. 

==Reference==
<ref group="xtra">PMID:19805289</ref><references group="xtra"/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Berger, J M.]]
[[Category: Dossani, Z Y.]]
[[Category: Erzberger, J P.]]
[[Category: Weirich, C S.]]
[[Category: Weis, K.]]
[[Category: Atp-binding]]
[[Category: Atpase]]
[[Category: Cytoplasm]]
[[Category: Helicase]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Mrna export]]
[[Category: Mrna transport]]
[[Category: Nuclear pore complex]]
[[Category: Nucleotide-binding]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protein transport]]
[[Category: Reca-fold]]
[[Category: Rna-binding]]
[[Category: Translocation]]
[[Category: Transport]]
<br />

=='''Content Donators'''==
Created with the participation of [[User:Eran Hodis|Eran Hodis]], [[User:Wayne Decatur|Wayne Decatur]].