View source for 8uzm


==Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (NADPH bound)==
<StructureSection load='8uzm' size='340' side='right'caption='[[8uzm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8uzm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_aerogenes_KCTC_2190 Klebsiella aerogenes KCTC 2190]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UZM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uzm OCA], [https://pdbe.org/8uzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uzm RCSB], [https://www.ebi.ac.uk/pdbsum/8uzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uzm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A447LC14_KLEAE A0A447LC14_KLEAE] Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.[HAMAP-Rule:MF_00804]
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</StructureSection>
[[Category: Klebsiella aerogenes KCTC 2190]]
[[Category: Large Structures]]
[[Category: Structural genomic]]