View source for 8q16


==CryoEM structure of rice nucleosome containing a H4 variant chimera==
<StructureSection load='8q16' size='340' side='right'caption='[[8q16]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8q16]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza Oryza] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q16 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q16 OCA], [https://pdbe.org/8q16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q16 RCSB], [https://www.ebi.ac.uk/pdbsum/8q16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q16 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/H2A2_ORYSI H2A2_ORYSI] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Oryza]]
[[Category: Synthetic construct]]
[[Category: Berger F]]
[[Category: Gireesh A]]
[[Category: Gut F]]
[[Category: Hari Sundar G V]]
[[Category: Jeyaprakash AA]]
[[Category: Jha S]]
[[Category: Raju S]]
[[Category: Shivaprasad PV]]
[[Category: Sotelo-Parrilla P]]
[[Category: Vinothkumar KR]]