View source for 8iw9


==Cryo-EM structure of the CAD-bound mTAAR9-Gs complex==
<StructureSection load='8iw9' size='340' side='right'caption='[[8iw9]], [[Resolution|resolution]] 3.08&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8iw9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IW9 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iw9 OCA], [https://pdbe.org/8iw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iw9 RCSB], [https://www.ebi.ac.uk/pdbsum/8iw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iw9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GBG2_HUMAN GBG2_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Synthetic construct]]
[[Category: Guo LL]]
[[Category: Li Q]]
[[Category: Lian S]]
[[Category: Rong NK]]
[[Category: Sun JP]]
[[Category: Xu YF]]
[[Category: Yang F]]
[[Category: Zhang MH]]