View source for 8f1i


==SigN RNA polymerase early-melted intermediate bound to mismatch fragment dhsU36mm1 (-12T)==
<StructureSection load='8f1i' size='340' side='right'caption='[[8f1i]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8f1i]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F1I FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f1i OCA], [https://pdbe.org/8f1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f1i RCSB], [https://www.ebi.ac.uk/pdbsum/8f1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f1i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]

==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Chen J]]
[[Category: Darst SA]]
[[Category: Mueller AU]]