View source for 8emx


==Phospholipase C beta 3 (PLCb3) in complex with Gbg on lipid nanodiscs==
<StructureSection load='8emx' size='340' side='right'caption='[[8emx]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8emx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EMX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8emx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8emx OCA], [https://pdbe.org/8emx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8emx RCSB], [https://www.ebi.ac.uk/pdbsum/8emx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8emx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLCB3_HUMAN PLCB3_HUMAN] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

==See Also==
*[[Phospholipase C|Phospholipase C]]
*[[Transducin 3D structures|Transducin 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Falzone ME]]
[[Category: MacKinnon R]]