View source for 7wkd


==TRH-TRHR G protein complex==
<StructureSection load='7wkd' size='340' side='right'caption='[[7wkd]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7wkd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WKD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LPD:L-PROLINAMIDE'>LPD</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wkd OCA], [https://pdbe.org/7wkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wkd RCSB], [https://www.ebi.ac.uk/pdbsum/7wkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wkd ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Cai H]]
[[Category: Cheng X]]
[[Category: He X]]
[[Category: Jiang H]]
[[Category: Jiang Y]]
[[Category: Xu HE]]
[[Category: Xu Y]]
[[Category: You C]]
[[Category: Yuan Q]]