View source for 7w9h


==Crystal structure of the receiver domain of the transcription regulator FleR from Pseudomonas aeruginosa==
<StructureSection load='7w9h' size='340' side='right'caption='[[7w9h]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7w9h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W9H FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w9h OCA], [https://pdbe.org/7w9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w9h RCSB], [https://www.ebi.ac.uk/pdbsum/7w9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w9h ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FLER_PSEAE FLER_PSEAE] Member of the two-component regulatory system FleS/FleR that regulates the expression of multiple genes involved in flagellar synthesis, adhesion, swarming, motility and antibiotic resistance (PubMed:7591148, PubMed:30877999, PubMed:8876537). May function as a transcriptional activator by direct binding to a cis-acting sequence upstream of the target genes (Probable).<ref>PMID:30877999</ref> <ref>PMID:7591148</ref> <ref>PMID:8876537</ref> <ref>PMID:7591148</ref> 

==See Also==
*[[Response regulator 3D structure|Response regulator 3D structure]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Jain D]]
[[Category: Sahoo PK]]
[[Category: Sheenu n]]