View source for 7qw5


==Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate unmethylated DNA duplex==
<StructureSection load='7qw5' size='340' side='right'caption='[[7qw5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7qw5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QW5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qw5 OCA], [https://pdbe.org/7qw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qw5 RCSB], [https://www.ebi.ac.uk/pdbsum/7qw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qw5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTC1_GEOSE MTC1_GEOSE] A gamma subtype methylase, recognizes the double-stranded sequence 5'-ATCGAT-3', methylation on A-5 on both strands, and protects the DNA from cleavage by the BanIII endonuclease.<ref>PMID:12654995</ref> 

==See Also==
*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Large Structures]]
[[Category: Bouriotis V]]
[[Category: Glykos NM]]
[[Category: Kokkinidis M]]
[[Category: Kotsifaki D]]
[[Category: Kouyianou K]]
[[Category: Mitsikas DA]]
[[Category: Providaki M]]