View source for 7l70


==The eukaryotic translation initiation factor 2B from Homo sapiens in its apo form==
<StructureSection load='7l70' size='340' side='right'caption='[[7l70]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7l70]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L70 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l70 OCA], [https://pdbe.org/7l70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l70 RCSB], [https://www.ebi.ac.uk/pdbsum/7l70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l70 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

==See Also==
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Boone M]]
[[Category: Frost A]]
[[Category: Lawrence R]]
[[Category: Schoof M]]
[[Category: Walter P]]
[[Category: Wang L]]