View source for 7b74


==Chimeric Streptavidin With A Dimerization Domain For Artificial Transfer Hydrogenation==
<StructureSection load='7b74' size='340' side='right'caption='[[7b74]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7b74]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_variant_bovis_AF2122/97 Mycobacterium tuberculosis variant bovis AF2122/97] and [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B74 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4IR:{N-(4-{[2-(AMINO-KAPPAN)ETHYL]SULFAMOYL-KAPPAN}PHENYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE}(CHLORO)[(1,2,3,4,5-ETA)-1,2,3,4,5-PENTAMETHYLCYCLOPENTADIENYL]IRIDIUM(III)'>4IR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b74 OCA], [https://pdbe.org/7b74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b74 RCSB], [https://www.ebi.ac.uk/pdbsum/7b74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b74 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).[https://www.uniprot.org/uniprot/SODC_MYCBO SODC_MYCBO] Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis variant bovis AF2122/97]]
[[Category: Streptomyces avidinii]]
[[Category: Igareta NV]]
[[Category: Ward TR]]