View source for 6ydv


==Crystal Structure of the Jmjc Domain of Human JMJD1B in complex with FM001511a from the DSPL fragment library==
<StructureSection load='6ydv' size='340' side='right'caption='[[6ydv]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ydv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YDV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ONQ:~{N}-(2-azanyl-2-oxidanylidene-ethyl)-4-methoxy-benzamide'>ONQ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ydv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ydv OCA], [https://pdbe.org/6ydv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ydv RCSB], [https://www.ebi.ac.uk/pdbsum/6ydv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ydv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A4FUT8_HUMAN A4FUT8_HUMAN] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.[RuleBase:RU369087]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Burgess-Brown NA]]
[[Category: Edwards AM]]
[[Category: Johansson C]]
[[Category: Nowak R]]
[[Category: Oppermann U]]
[[Category: Snee M]]