View source for 6sd6


==Structure of VapBC from Shigella sonnei==
<StructureSection load='6sd6' size='340' side='right'caption='[[6sd6]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6sd6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_sonnei Shigella sonnei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SD6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sd6 OCA], [https://pdbe.org/6sd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sd6 RCSB], [https://www.ebi.ac.uk/pdbsum/6sd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sd6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H9P9N5_SHISO A0A0H9P9N5_SHISO] Toxic component of a toxin-antitoxin (TA) system. A site-specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Its toxic effects are neutralized by expression of cognate antitoxin VapB.[HAMAP-Rule:MF_00265]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Shigella sonnei]]
[[Category: Hollingshead S]]
[[Category: Lea SM]]