View source for 6rsb


==Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class==
<StructureSection load='6rsb' size='340' side='right'caption='[[6rsb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RSB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KGZ:1-[(3~{R},4~{R})-4-(cyanomethyl)-1-[[4-(cyclohexen-1-yl)phenyl]methyl]-3-fluoranyl-piperidin-4-yl]-3-(cyclopropylcarbonylamino)pyrazole-4-carboxamide'>KGZ</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rsb OCA], [https://pdbe.org/6rsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rsb RCSB], [https://www.ebi.ac.uk/pdbsum/6rsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rsb ProSAT]</span></td></tr>
</table>

==See Also==
*[[Janus kinase 3D structures|Janus kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Brown DG]]
[[Category: Lupardus PJ]]