View source for 6new


==Apo structure of the activated truncation of Vav1==
<StructureSection load='6new' size='340' side='right'caption='[[6new]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6new]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NEW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6new FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6new OCA], [https://pdbe.org/6new PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6new RCSB], [https://www.ebi.ac.uk/pdbsum/6new PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6new ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VAV_HUMAN VAV_HUMAN] Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Elling RA]]
[[Category: Knapp MS]]
[[Category: Ornelas E]]