View source for 6jrr


==Structure of RyR2 (*F/A/C/L-Ca2+ dataset)==
<SX load='6jrr' size='340' side='right' viewer='molstar' caption='[[6jrr]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jrr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JRR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CFF:CAFFEINE'>CFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jrr OCA], [https://pdbe.org/6jrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jrr RCSB], [https://www.ebi.ac.uk/pdbsum/6jrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jrr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FKB1B_HUMAN FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

==See Also==
*[[FKBP 3D structures|FKBP 3D structures]]
*[[Ryanodine receptor 3D structures|Ryanodine receptor 3D structures]]
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</SX>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Chi XM]]
[[Category: Gong DS]]
[[Category: Huang GXY]]
[[Category: Lei JL]]
[[Category: Yan N]]
[[Category: Zhou GW]]