View source for 6iy2


==Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state==
<SX load='6iy2' size='340' side='right' viewer='molstar' caption='[[6iy2]], [[Resolution|resolution]] 3.47&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6iy2]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IY2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.47&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iy2 OCA], [https://pdbe.org/6iy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iy2 RCSB], [https://www.ebi.ac.uk/pdbsum/6iy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iy2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

==See Also==
*[[Helicase 3D structures|Helicase 3D structures]]
*[[Histone 3D structures|Histone 3D structures]]
__TOC__
</SX>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Xenopus laevis]]
[[Category: Chen Z]]
[[Category: Li M]]
[[Category: Li X]]
[[Category: Liu X]]
[[Category: Xia X]]