View source for 6e0t


==C-terminal domain of Fission Yeast OFD1==
<StructureSection load='6e0t' size='340' side='right'caption='[[6e0t]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6e0t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E0T FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0t OCA], [https://pdbe.org/6e0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e0t RCSB], [https://www.ebi.ac.uk/pdbsum/6e0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OFD1_SCHPO OFD1_SCHPO] Prolyl 3,4-dihydroxylase that catalyzes 3,4-dihydroxylation of 'Pro-62' of small ribosomal subunit uS12 (rps23 and rps2302), thereby regulating protein translation termination efficiency. Negative regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which is released from the membrane and enters the nucleus to activate hypoxic gene expression.<ref>PMID:19158663</ref> <ref>PMID:24550462</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Amzel LM]]
[[Category: Bianchet MA]]
[[Category: Espenshade PJ]]
[[Category: Yeh T]]