View source for 6drv


==Beta-galactosidase==
<SX load='6drv' size='340' side='right' viewer='molstar' caption='[[6drv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6drv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DRV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6drv OCA], [https://pdbe.org/6drv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6drv RCSB], [https://www.ebi.ac.uk/pdbsum/6drv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6drv ProSAT]</span></td></tr>
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== Function ==
[https://www.uniprot.org/uniprot/BGAL_ECOLI BGAL_ECOLI] 
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== Publication Abstract from PubMed ==
Access to streamlined computational resources remains a significant bottleneck for new users of cryo-electron microscopy (cryo-EM). To address this, we have developed tools that will submit cryo-EM analysis routines and atomic model building jobs directly to Amazon Web Services (AWS) from a local computer or laptop. These new software tools ("cryoem-cloud-tools") have incorporated optimal data movement, security, and cost-saving strategies, giving novice users access to complex cryo-EM data processing pipelines. Integrating these tools into the RELION processing pipeline and graphical user interface we determined a 2.2A structure of ss-galactosidase in approximately 55h on AWS. We implemented a similar strategy to submit Rosetta atomic model building and refinement to AWS. These software tools dramatically reduce the barrier for entry of new users to cloud computing for cryo-EM and are freely available at cryoem-tools.cloud.

cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud.,Cianfrocco MA, Lahiri I, DiMaio F, Leschziner AE J Struct Biol. 2018 Jun 1. pii: S1047-8477(18)30138-2. doi:, 10.1016/j.jsb.2018.05.014. PMID:29864529<ref>PMID:29864529</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 6drv" style="background-color:#fffaf0;"></div>

==See Also==
*[[Galactosidase 3D structures|Galactosidase 3D structures]]
== References ==
<references/>
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</SX>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Cianfrocco MA]]
[[Category: DiMaio F]]
[[Category: Lahiri I]]
[[Category: Leschziner AE]]