View source for 6blb


==1.88 Angstrom Resolution Crystal Structure Holliday Junction ATP-dependent DNA Helicase (RuvB) from Pseudomonas aeruginosa in Complex with ADP==
<StructureSection load='6blb' size='340' side='right'caption='[[6blb]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6blb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BLB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6blb OCA], [https://pdbe.org/6blb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6blb RCSB], [https://www.ebi.ac.uk/pdbsum/6blb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6blb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RUVB_PSEAE RUVB_PSEAE] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.[HAMAP-Rule:MF_00016]

==See Also==
*[[Helicase 3D structures|Helicase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Anderson WF]]
[[Category: Dubrovska I]]
[[Category: Grimshaw S]]
[[Category: Joachimiak A]]
[[Category: Kiryukhina O]]
[[Category: Kwon K]]
[[Category: Minasov G]]
[[Category: Satchell KJF]]
[[Category: Shuvalova L]]