View source for 5y65


==Phosphoglycerate mutase 1 complexed with a small molecule inhibitor KH2==
<StructureSection load='5y65' size='340' side='right'caption='[[5y65]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5y65]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y65 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5Y65 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HKB:~{N}-[3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen-2-yl]-4-(dimethylamino)benzenesulfonamide'>HKB</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5y65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y65 OCA], [http://pdbe.org/5y65 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y65 RCSB], [http://www.ebi.ac.uk/pdbsum/5y65 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y65 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. 

==See Also==
*[[Phosphoglycerate mutase 3D structures|Phosphoglycerate mutase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Jiang, L L]]
[[Category: Zhou, L]]
[[Category: Isomerase-inhibitor complex]]
[[Category: Phosphoglycerate mutase]]