View source for 5wwl


==Crystal structure of the Schizogenesis pombe kinetochore Mis12C subcomplex==
<StructureSection load='5wwl' size='340' side='right'caption='[[5wwl]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5wwl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WWL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wwl OCA], [https://pdbe.org/5wwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wwl RCSB], [https://www.ebi.ac.uk/pdbsum/5wwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wwl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MIS12_SCHPO MIS12_SCHPO] Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct segregation of chromosomes and for maintaining the inner centromere structure.<ref>PMID:12773390</ref> 

==See Also==
*[[Centromere protein 3D structure|Centromere protein 3D structure]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Wang C]]
[[Category: Wu M]]
[[Category: Zang J]]
[[Category: Zhang X]]
[[Category: Zhou X]]