View source for 5una


==Fragment of 7SK snRNA methylphosphate capping enzyme==
<StructureSection load='5una' size='340' side='right'caption='[[5una]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5una]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3g07 3g07]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UNA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UNA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5je2|5je2]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MEPCE, BCDIN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5una FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5una OCA], [http://pdbe.org/5una PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5una RCSB], [http://www.ebi.ac.uk/pdbsum/5una PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5una ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/MEPCE_HUMAN MEPCE_HUMAN]] S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.<ref>PMID:17643375</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Dombrovski, L]]
[[Category: Edwards, A M]]
[[Category: Loppnau, P]]
[[Category: McCarthy, A A]]
[[Category: Park, H]]
[[Category: Structural genomic]]
[[Category: Tempel, W]]
[[Category: Wu, H]]
[[Category: Methyltransferase]]
[[Category: Transferase]]