View source for 5tao


==Haloferax volcanii Malate Synthase Lead(II) complex==
<StructureSection load='5tao' size='340' side='right'caption='[[5tao]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5tao]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloferax_volcanii_DS2 Haloferax volcanii DS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TAO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLV:GLYOXYLIC+ACID'>GLV</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tao OCA], [https://pdbe.org/5tao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tao RCSB], [https://www.ebi.ac.uk/pdbsum/5tao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tao ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACEB_HALVD ACEB_HALVD] Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA.<ref>PMID:11513957</ref> <ref>PMID:21569248</ref> <ref>PMID:9738442</ref> 

==See Also==
*[[Malate synthase 3D structures|Malate synthase 3D structures]]
== References ==
<references/>
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</StructureSection>
[[Category: Haloferax volcanii DS2]]
[[Category: Large Structures]]
[[Category: Adams MJ]]
[[Category: Howard BR]]