View source for 5sbp


==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z1229798311==
<StructureSection load='5sbp' size='340' side='right'caption='[[5sbp]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5sbp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SBP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.275&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8BC:2-acetamido-6-fluorobenzoic+acid'>8BC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sbp OCA], [https://pdbe.org/5sbp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sbp RCSB], [https://www.ebi.ac.uk/pdbsum/5sbp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sbp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Bezerra GA]]
[[Category: Bountra C]]
[[Category: Bradshaw WJ]]
[[Category: Brennan PE]]
[[Category: Gileadi O]]
[[Category: Katis VL]]
[[Category: Koekemoer L]]
[[Category: Von Delft F]]