View source for 5nfs


==Structure of coxsackievirus B3 3C protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide (cinnamoyl-phenylalanine-GlnLactam-CO-CO-NH-benzyl)==
<StructureSection load='5nfs' size='340' side='right'caption='[[5nfs]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5nfs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_B3 Coxsackievirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NFS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D03:(2~{S},3~{S})-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-~{N}-(phenylmethyl)-3-[[(2~{S})-3-phenyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanoyl]amino]butanamide'>D03</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nfs OCA], [https://pdbe.org/5nfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nfs RCSB], [https://www.ebi.ac.uk/pdbsum/5nfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nfs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5UEA2_9ENTO Q5UEA2_9ENTO] 

==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
</StructureSection>
[[Category: Coxsackievirus B3]]
[[Category: Large Structures]]
[[Category: Hilgenfeld R]]
[[Category: Ma Q]]
[[Category: Zhang L]]