View source for 5mlg


==Crystal structure of rat prorenin==
<StructureSection load='5mlg' size='340' side='right'caption='[[5mlg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5mlg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MLG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MLG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mlg OCA], [https://pdbe.org/5mlg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mlg RCSB], [https://www.ebi.ac.uk/pdbsum/5mlg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mlg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RENI_RAT RENI_RAT] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

==See Also==
*[[Renin|Renin]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Read R]]
[[Category: Yan Y]]