View source for 5i2b


==Crystal structure of a peptide deformylase from Burkholderia ambifaria with actinonin==
<StructureSection load='5i2b' size='340' side='right'caption='[[5i2b]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5i2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_ambifaria_IOP40-10 Burkholderia ambifaria IOP40-10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I2B FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i2b OCA], [https://pdbe.org/5i2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i2b RCSB], [https://www.ebi.ac.uk/pdbsum/5i2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i2b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B1FPK4_9BURK B1FPK4_9BURK] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
__TOC__
</StructureSection>
[[Category: Burkholderia ambifaria IOP40-10]]
[[Category: Large Structures]]