View source for 5dk6


==CRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH) NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) IN COMPLEX WITH ADENINE AT 2.27 A RESOLUTION==
<StructureSection load='5dk6' size='340' side='right'caption='[[5dk6]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5dk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Colwellia_psychrerythraea_34H Colwellia psychrerythraea 34H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DK6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dk6 OCA], [https://pdbe.org/5dk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dk6 RCSB], [https://www.ebi.ac.uk/pdbsum/5dk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dk6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTNN_COLP3 MTNN_COLP3] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[HAMAP-Rule:MF_01684]
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</StructureSection>
[[Category: Colwellia psychrerythraea 34H]]
[[Category: Large Structures]]
[[Category: Ahmed M]]
[[Category: Almo SC]]
[[Category: Bhosle R]]
[[Category: Bonanno JB]]
[[Category: Celikgil A]]
[[Category: Chamala S]]
[[Category: Chan MK]]
[[Category: Evans B]]
[[Category: Fiser A]]
[[Category: Garforth S]]
[[Category: Gizzi A]]
[[Category: Hillerich B]]
[[Category: Himmel DM]]
[[Category: Kar A]]
[[Category: Lafluer J]]
[[Category: Lim S]]
[[Category: Love J]]
[[Category: Matikainen B]]
[[Category: Patel H]]
[[Category: Seidel RD]]
[[Category: Toro R]]
[[Category: Villegas G]]