View source for 4x51


==X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y==
<StructureSection load='4x51' size='340' side='right'caption='[[4x51]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4x51]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X51 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X51 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x51 OCA], [https://pdbe.org/4x51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x51 RCSB], [https://www.ebi.ac.uk/pdbsum/4x51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x51 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IL10_MOUSE IL10_MOUSE] Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

==See Also==
*[[Interleukin 3D structures|Interleukin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Kuenze G]]