View source for 4wml


==Crystal structure of Saccharomyces cerevisiae OMP synthase in complex with PRP(CH2)P==
<StructureSection load='4wml' size='340' side='right'caption='[[4wml]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4wml]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WML FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PPC:5-PHOSPHORIBOSYL-1-(BETA-METHYLENE)+PYROPHOSPHATE'>PPC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wml OCA], [https://pdbe.org/4wml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wml RCSB], [https://www.ebi.ac.uk/pdbsum/4wml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wml ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRE_YEAST PYRE_YEAST] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).[HAMAP-Rule:MF_01208]

==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Bang MB]]
[[Category: Grubmeyer C]]
[[Category: Hansen MR]]
[[Category: Harris P]]
[[Category: Molich U]]