View source for 4tps


==Sporulation Inhibitor of DNA Replication, SirA, in complex with Domain I of DnaA==
<StructureSection load='4tps' size='340' side='right'caption='[[4tps]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4tps]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TPS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tps OCA], [https://pdbe.org/4tps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tps RCSB], [https://www.ebi.ac.uk/pdbsum/4tps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tps ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SIRA_BACSU SIRA_BACSU] Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation.

==See Also==
*[[DnaA|DnaA]]
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Fogg MJ]]
[[Category: Grahl A]]
[[Category: Jameson KH]]
[[Category: Turkenburg JP]]
[[Category: Wilkinson AJ]]