View source for 4ohc


==Crystal structure of orotate phosphoribosyltransferase (OPRTase) from Burkholderia cenocepacia==
<StructureSection load='4ohc' size='340' side='right'caption='[[4ohc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ohc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OHC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ohc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ohc OCA], [https://pdbe.org/4ohc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ohc RCSB], [https://www.ebi.ac.uk/pdbsum/4ohc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ohc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B4E589_BURCJ B4E589_BURCJ] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).[HAMAP-Rule:MF_01208][SAAS:SAAS004467_004_016272]

==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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</StructureSection>
[[Category: Burkholderia cenocepacia J2315]]
[[Category: Large Structures]]