View source for 4np5


==Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A/I92N at cryogenic temperature==
<StructureSection load='4np5' size='340' side='right'caption='[[4np5]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4np5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4eoa 4eoa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NP5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4np5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4np5 OCA], [https://pdbe.org/4np5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4np5 RCSB], [https://www.ebi.ac.uk/pdbsum/4np5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4np5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

==See Also==
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Caro JA]]
[[Category: Garcia-Moreno E B]]
[[Category: Heroux A]]
[[Category: Nam S]]
[[Category: Schlessman JL]]