View source for 4jfj


==Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound (1S,6R)-10-(1,3-benzothiazol-6-ylsulfonyl)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one==
<StructureSection load='4jfj' size='340' side='right'caption='[[4jfj]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4jfj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JFJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1KU:(1S,6R)-10-(1,3-BENZOTHIAZOL-6-YLSULFONYL)-3-[2-(3,4-DIMETHOXYPHENOXY)ETHYL]-3,10-DIAZABICYCLO[4.3.1]DECAN-2-ONE'>1KU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jfj OCA], [https://pdbe.org/4jfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jfj RCSB], [https://www.ebi.ac.uk/pdbsum/4jfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jfj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.

==See Also==
*[[FKBP 3D structures|FKBP 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bracher A]]
[[Category: Fabian A]]
[[Category: Gopalakrishnan R]]
[[Category: Hausch F]]
[[Category: Hoogeland B]]
[[Category: Kirschner A]]
[[Category: Koch U]]
[[Category: Kozany C]]
[[Category: Kress C]]
[[Category: Wang Y]]