View source for 4j39


==Crystal structure of p19 in complex with double-helical 19mer RNA p(CAG)3C(CUG)3==
<StructureSection load='4j39' size='340' side='right'caption='[[4j39]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4j39]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J39 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j39 OCA], [https://pdbe.org/4j39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j39 RCSB], [https://www.ebi.ac.uk/pdbsum/4j39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j39 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).

==See Also==
*[[P19|P19]]
*[[RNA silencing suppressor|RNA silencing suppressor]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Tomato bushy stunt virus]]
[[Category: Malinina L]]
[[Category: Popov AN]]
[[Category: Tamjar J]]