View source for 3tlx


==Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum==
<StructureSection load='3tlx' size='340' side='right'caption='[[3tlx]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tlx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlx OCA], [https://pdbe.org/3tlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlx RCSB], [https://www.ebi.ac.uk/pdbsum/3tlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KAD1_PLAF7 KAD1_PLAF7] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (PubMed:15478799). Has very low activity with CTP, GTP, ITP and UTP and no activity with GMP, CMP, UMP or IMP in vitro (PubMed:15478799).<ref>PMID:15478799</ref> 

==See Also==
*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Amani M]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Crombet L]]
[[Category: Edwards AM]]
[[Category: Hui R]]
[[Category: Loppnau P]]
[[Category: Park H]]
[[Category: Perieteanu A]]
[[Category: Weadge J]]
[[Category: Wernimont AK]]