View source for 3tlm


==Crystal Structure of Endoplasmic Reticulum Ca2+-ATPase (SERCA) From Bovine Muscle==
<StructureSection load='3tlm' size='340' side='right'caption='[[3tlm]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tlm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlm OCA], [https://pdbe.org/3tlm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlm RCSB], [https://www.ebi.ac.uk/pdbsum/3tlm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AT2A1_BOVIN AT2A1_BOVIN] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Bertipaglia I]]
[[Category: Carafoli E]]
[[Category: Cendron L]]
[[Category: Damiani E]]
[[Category: Giannetti S]]
[[Category: Mascarello F]]
[[Category: Sacchetto R]]
[[Category: Zanotti G]]