View source for 3j07


==Model of a 24mer alphaB-crystallin multimer==
<SX load='3j07' size='340' side='right' viewer='molstar' caption='[[3j07]], [[Resolution|resolution]] 20.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3j07]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J07 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J07 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy , Hybrid , Solid-state NMR , X-ray solution scattering, [[Resolution|Resolution]] 20&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j07 OCA], [https://pdbe.org/3j07 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j07 RCSB], [https://www.ebi.ac.uk/pdbsum/3j07 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j07 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.

==See Also==
*[[Crystallin 3D structures|Crystallin 3D structures]]
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</SX>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bardiaux B]]
[[Category: Dove KK]]
[[Category: Gonen T]]
[[Category: Jehle S]]
[[Category: Klevit RE]]
[[Category: Oschkinat H]]
[[Category: Rajagopal P]]
[[Category: Vollmar B]]