View source for 2xvt


==Structure of the extracellular domain of human RAMP2==
<StructureSection load='2xvt' size='340' side='right'caption='[[2xvt]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2xvt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XVT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xvt OCA], [https://pdbe.org/2xvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xvt RCSB], [https://www.ebi.ac.uk/pdbsum/2xvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xvt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAMP2_HUMAN RAMP2_HUMAN] Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.<ref>PMID:22102369</ref> <ref>PMID:9620797</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Barr AJ]]
[[Category: Bountra C]]
[[Category: Burgess-Brown N]]
[[Category: Canning P]]
[[Category: Carpenter EP]]
[[Category: Chaikuad A]]
[[Category: Das S]]
[[Category: Edwards AM]]
[[Category: Goubin S]]
[[Category: Kim J]]
[[Category: Krojer T]]
[[Category: Muniz JRC]]
[[Category: Pike ACW]]
[[Category: Quigley A]]
[[Category: Shrestha L]]
[[Category: Vollmar M]]
[[Category: Weigelt J]]
[[Category: Von Delft F]]