View source for 2pt5


==Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5==
<StructureSection load='2pt5' size='340' side='right'caption='[[2pt5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2pt5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PT5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pt5 OCA], [https://pdbe.org/2pt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2pt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pt5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2pt5 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROK_AQUAE AROK_AQUAE] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pt/2pt5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pt5 ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Shikimate kinase 3D structures|Shikimate kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus VF5]]
[[Category: Large Structures]]
[[Category: Ebihara A]]
[[Category: Jeyakanthan J]]
[[Category: Kuramitsu S]]
[[Category: Nithya N]]
[[Category: Shimada A]]
[[Category: Shinkai A]]
[[Category: Shiro Y]]
[[Category: Velmurugan D]]
[[Category: Yokoyama S]]