View source for 2n83


==p75NTR DD:RIP2 CARD==
<StructureSection load='2n83' size='340' side='right'caption='[[2n83]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2n83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N83 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n83 OCA], [https://pdbe.org/2n83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n83 RCSB], [https://www.ebi.ac.uk/pdbsum/2n83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n83 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TNR16_HUMAN TNR16_HUMAN] Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.<ref>PMID:14966521</ref> 

==See Also==
*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ibanez CF]]
[[Category: Lin Z]]