View source for 2my1


==Solution structure of Bud31p==
<StructureSection load='2my1' size='340' side='right'caption='[[2my1]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2my1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MY1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2my1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2my1 OCA], [https://pdbe.org/2my1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2my1 RCSB], [https://www.ebi.ac.uk/pdbsum/2my1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2my1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BUD31_YEAST BUD31_YEAST] Involved in pre-mRNA splicing. Important for bud site selection.
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Establishing the binding topology of structural zinc ions in proteins is an essential part of their structure determination by NMR spectroscopy. Using 113 Cd NMR experiments with 113 Cd-substituted samples is a useful approach but has previously been limited mainly to very small protein domains. Here we used 113 Cd NMR spectroscopy during structure determination of Bud31p, a 157-residue yeast protein containing an unusual Zn3 Cys9 cluster, demonstrating that recent hardware developments make this approach feasible for significantly larger systems.

Cd NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p.,van Roon AM, Yang JC, Mathieu D, Bermel W, Nagai K, Neuhaus D Angew Chem Int Ed Engl. 2015 Feb 20. doi: 10.1002/anie.201412210. PMID:25703931<ref>PMID:25703931</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2my1" style="background-color:#fffaf0;"></div>

==See Also==
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Bermel W]]
[[Category: Mathieu D]]
[[Category: Nagai K]]
[[Category: Neuhaus D]]
[[Category: Yang J]]
[[Category: Van Roon AM]]