View source for 2ld5


==Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA==
<StructureSection load='2ld5' size='340' side='right'caption='[[2ld5]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ld5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LD5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ld5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ld5 OCA], [https://pdbe.org/2ld5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ld5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ld5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ld5 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/HXA13_MOUSE HXA13_MOUSE] Defects in Hoxa13 are the cause of hypodactyly (Hd), a condition characterized by profound deficiency of digital arch structures.
== Function ==
[https://www.uniprot.org/uniprot/HXA13_MOUSE HXA13_MOUSE] Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity).

==See Also==
*[[Hox protein|Hox protein]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Zhang Y]]