View source for 1tos


==TORPEDO CALIFORNICA ACHR RECEPTOR [ALA76] ANALOGUE COMPLEXED WITH THE ANTI-ACETYLCHOLINE MAB6 MONOCLONAL ANTIBODY==
<StructureSection load='1tos' size='340' side='right'caption='[[1tos]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1tos]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TOS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tos OCA], [https://pdbe.org/1tos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tos RCSB], [https://www.ebi.ac.uk/pdbsum/1tos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tos ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACHA_TETCF ACHA_TETCF] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Tetronarce californica]]
[[Category: Cung MT]]
[[Category: Marraud M]]
[[Category: Orlewski P]]
[[Category: Sakarellos C]]
[[Category: Sakarellos-Daistiotis M]]
[[Category: Tsikaris V]]
[[Category: Tzartos SJ]]
[[Category: Vatzaki E]]