View source for 1ocy

[[Image:1ocy.gif|left|200px]]<br />
<applet load="1ocy" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="1ocy, resolution 1.500&Aring;" />
'''STRUCTURE OF THE RECEPTOR-BINDING DOMAIN OF THE BACTERIOPHAGE T4 SHORT TAIL FIBRE'''<br />

==Overview==
Adsorption of T4 bacteriophage to the Escherichia coli host cell is, mediated by six long and six short tail fibres. After at least three long, tail fibres have bound, short tail fibres extend and bind irreversibly to, the core region of the host cell lipo-polysaccharide (LPS), serving as, inextensible stays during penetration of the cell envelope by the tail, tube. The short tail fibres consist of a parallel, in-register, trimer of, gene product 12 (gp12).X-ray crystallography at 1.5A resolution of a, protease-stable fragment of gp12 generated in the presence of zinc, chloride reveals the structure of the C-terminal receptor-binding domain., It has a novel "knitted" fold, consisting of three extensively intertwined, monomers. It reveals a metal-binding site, containing a zinc ion, ... [[http://ispc.weizmann.ac.il/pmbin/getpm?12888344 (full description)]]

==About this Structure==
1OCY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacteriophage_t4 Bacteriophage t4]] with SO4, ZN and CIT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OCY OCA]]. 

==Reference==
The structure of the receptor-binding domain of the bacteriophage T4 short tail fibre reveals a knitted trimeric metal-binding fold., Thomassen E, Gielen G, Schutz M, Schoehn G, Abrahams JP, Miller S, van Raaij MJ, J Mol Biol. 2003 Aug 8;331(2):361-73. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12888344 12888344]
[[Category: Bacteriophage t4]]
[[Category: Single protein]]
[[Category: Gielen, G.]]
[[Category: Miller, S.]]
[[Category: Raaij, M.J.Van.]]
[[Category: Schuetz, M.]]
[[Category: Thomassen, E.]]
[[Category: CIT]]
[[Category: SO4]]
[[Category: ZN]]
[[Category: bacteriophage structural protein]]
[[Category: baseplate protein]]
[[Category: fibrous protein]]
[[Category: gene product 12]]
[[Category: lipo-polysaccharide binding]]

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