View source for 1urw

{{Seed}}
[[Image:1urw.png|left|200px]]

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{{STRUCTURE_1urw|  PDB=1urw  |  SCENE=  }} 

===CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-B]PYRIDAZINE===


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{{ABSTRACT_PUBMED_15081018}}

==About this Structure==
1URW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URW OCA]. 

==Reference==
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors., Byth KF, Cooper N, Culshaw JD, Heaton DW, Oakes SE, Minshull CA, Norman RA, Pauptit RA, Tucker JA, Breed J, Pannifer A, Rowsell S, Stanway JJ, Valentine AL, Thomas AP, Bioorg Med Chem Lett. 2004 May 3;14(9):2249-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15081018 15081018]

High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design., Schulze-Gahmen U, De Bondt HL, Kim SH, J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8917641 8917641]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Breed, J.]]
[[Category: Byth, K F.]]
[[Category: Cooper, N.]]
[[Category: Culshaw, J D.]]
[[Category: Heaton, D W.]]
[[Category: Minshull, C A.]]
[[Category: Norman, R A.]]
[[Category: Oakes, S E.]]
[[Category: Pannifer, A.]]
[[Category: Pauptit, R A.]]
[[Category: Rowsell, S.]]
[[Category: Stanway, J J.]]
[[Category: Thomas, A P.]]
[[Category: Tucker, J A.]]
[[Category: Valentine, A L.]]
[[Category: Mitosis]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 09:03:53 2008''