View source for 1rs2

{{Seed}}
[[Image:1rs2.png|left|200px]]

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{{STRUCTURE_1rs2|  PDB=1rs2  |  SCENE=  }} 

===DHNA complex with 8-Amino-1,3-dimethyl-3,7-dihydropurine-2,6-dione===


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{{ABSTRACT_PUBMED_15027862}}

==About this Structure==
1RS2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RS2 OCA]. 

==Reference==
Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization., Sanders WJ, Nienaber VL, Lerner CG, McCall JO, Merrick SM, Swanson SJ, Harlan JE, Stoll VS, Stamper GF, Betz SF, Condroski KR, Meadows RP, Severin JM, Walter KA, Magdalinos P, Jakob CG, Wagner R, Beutel BA, J Med Chem. 2004 Mar 25;47(7):1709-18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15027862 15027862]
[[Category: Dihydroneopterin aldolase]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Betz, S F.]]
[[Category: Beutel, B A.]]
[[Category: Condroski, K R.]]
[[Category: Harlan, J E.]]
[[Category: Jakob, C G.]]
[[Category: Lerner, C G.]]
[[Category: Magdalinos, P.]]
[[Category: McCall, J O.]]
[[Category: Meadows, R P.]]
[[Category: Merrick, S M.]]
[[Category: Nienaber, V L.]]
[[Category: Sanders, W J.]]
[[Category: Severin, J M.]]
[[Category: Stamper, G F.]]
[[Category: Stoll, V S.]]
[[Category: Swanson, S J.]]
[[Category: Wagner, R.]]
[[Category: Walter, K A.]]
[[Category: 7,8-dihydroneop8-amino-1,3-dimethyl-3,7-dihydropurine-2,6-dioneterin aldolase]]
[[Category: Dhna]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:03:01 2008''